Concise Summary for Procurement

Catalog ID

Compound

Overview

MOTS-RES-016

MOTS-c (Mitochondrial Derived Peptide)

A 16-amino acid peptide encoded by the mitochondrial 12S rRNA gene. Functions as a potent regulator of metabolic homeostasis, activating AMPK to promote glucose uptake and fatty acid oxidation. Widely used in research on obesity, aging, and muscle metabolism.

• Form: White Lyophilized Powder
• Storage: Store at -20°C (lyophilized).
• Purity: >98%

Safety Note

This is a Bioactive Peptide. The Buyer assumes all responsibility for safe handling and proper disposal in accordance with applicable regulations and best laboratory practices.

Detailed Product Specification and Handling Protocol

I. Product Identification

Field

Detail

Compound Name

MOTS-c (Mitochondrial Derived Peptide)

Catalog ID

MOTS-RES-016

Sequence

[16-amino acid sequence placeholder]

Molecular Formula

[Molecular formula placeholder]

Molecular Weight

[Molecular weight placeholder]

II. Chemical and Physical Properties

The MOTS-c peptide is supplied as a white lyophilized powder, ensuring stability and long-term storage capability.

• Purity: Guaranteed at >98% (verified by HPLC).
• Solubility: Soluble in water, PBS, or other aqueous buffers. For reconstitution, it is recommended to add the desired solvent slowly and mix gently. Avoid aggressive vortexing.
• Appearance: Fine, white powder.

III. Storage, Stability, and Handling

A. Lyophilized Form Storage

For maximum shelf life and stability, the peptide must be stored as specified below:

• Temperature: -20°C is the recommended long-term storage temperature.
• Condition: Keep the container tightly sealed and protected from light and moisture. Storage in a desiccated environment is strongly advised.

B. Reconstituted Solution Storage

Once reconstituted, the peptide solution requires careful handling:

Solvent

Reconstitution Recommendation

Short-Term Storage

Long-Term Storage

Water/Buffer

Reconstitute to desired working concentration.

4°C for up to 1-2 weeks.

Aliquot and store at -20°C or -80°C. Avoid multiple freeze-thaw cycles.

C. Handling Precautions

• Use standard laboratory personal protective equipment (PPE), including lab coats, gloves, and eye protection.
• Work in a well-ventilated area or under a chemical fume hood when handling the powder or concentrated solutions.

IV. Research Applications and Mechanism of Action

A. Primary Research Focus

MOTS-c is a critical subject in research due to its involvement in key metabolic and cellular processes:

1. Metabolic Homeostasis: Regulation of whole-body energy balance.
2. Obesity and Insulin Sensitivity: Improvement of glucose metabolism and reduction of insulin resistance.
3. Aging: Potential role as a longevity factor by promoting mitochondrial health.
4. Muscle Metabolism: Influence on muscle function and preservation.

B. Mechanism of Action Summary

MOTS-c primarily exerts its effects by acting as a potent activator of AMP-activated protein kinase (AMPK). This activation leads to a cascade of metabolic effects:

• Enhanced Glucose Uptake: Stimulates the translocation of glucose transporters to the cell membrane.
• Increased Fatty Acid Oxidation: Promotes the breakdown of fats for energy, potentially reducing ectopic lipid accumulation.

V. Quality Control Documentation

This lot (MOTS-RES-016) has passed rigorous quality control standards to ensure high purity and identity.

A. Certificate of Analysis (CoA)

A comprehensive Certificate of Analysis is available for download at the following location: File.

Test

Method

Specification

Result (Lot MOTS-RES-016)

Purity

HPLC

>98%

[Purity result placeholder]

Mass Identity

MS (Mass Spectrometry)

Consistent with theoretical mass

Passes

Appearance

Visual Inspection

White Lyophilized Powder

Passes

Water Content

Karl Fischer Titration

<5%

[Water content result placeholder]

B. Example of QC Data

The image below represents the typical result from the High-Performance Liquid Chromatography (HPLC) testing used to determine the purity of this compound. The purity measurement is crucial for accurate experimental dosing.

VI. Regulatory and Safety Information

A. Intended Use and Restrictions

MOTS-c (Catalog ID: MOTS-RES-016) is strictly for Research Use Only (RUO). It is not intended for use in humans, clinical trials, or as a diagnostic agent.

B. Material Safety Data Sheet (MSDS)

The complete Material Safety Data Sheet, detailing hazard identification, first-aid measures, and safe handling procedures, can be accessed here: File.

C. Disposal

Dispose of unused peptide and waste in accordance with local, state, and federal hazardous waste regulations. Consult the MSDS for specific guidelines.

VII. Ordering and Procurement Details

A. Ordering Information

For placement of a new purchase order or to check current stock levels, please contact the procurement liaison at Person via email at [email address placeholder].

Item

Catalog ID

Unit Size Options

Current Pricing

MOTS-c Peptide

MOTS-RES-016

[Size 1 placeholder]

[Price 1 placeholder]

MOTS-c Peptide

MOTS-RES-016

[Size 2 placeholder]

[Price 2 placeholder]

B. Shipping and Logistics

Shipping Condition

Carrier

Estimated Lead Time

Tracking Information

Blue Ice/Cold Pack

[Carrier placeholder]

[Lead time placeholder]

Available via link in order confirmation email.

VIII. Emergency Contact and Support

In the event of an emergency involving the handling or accidental exposure to MOTS-c, please follow the protocol below.

• Internal Emergency Contact: Person (Extension: [extension placeholder])
• External Chemical Emergency: Contact local Poison Control Center or emergency services.

For technical questions regarding reconstitution or application, contact Research Support at [support email placeholder].

IX. Vendor Information

Vendor Name

[Vendor name placeholder]

Primary Contact

Person

Address

Place

Customer Service Line

[Phone number placeholder]

Website

[Website link placeholder]

X. Procurement Approval Log

This section documents the required approvals for the purchase of Catalog ID MOTS-RES-016.

Role

Name

Signature/Date

Principal Investigator

Person

Date

Lab Manager

Person

Date

Procurement Officer

Person

Date