AOD9604

1. Compound Identification

1.1 Product Name

AOD9604 (Research Grade)

1.2 Sequence Origin

Modified fragment of Insulin-like Growth Factor Binding Protein 3 (IGFBP-3) segment 194-217.

1.3 Molecular Description

AOD9604 is a synthetically modified derivative of the C-terminal segment (residues 194-217) of the human growth hormone (hGH) molecule, which has been shown to be the key lipolytic and anti-lipogenic region of the hGH molecule. This modification stabilizes the molecule, enhancing its metabolic stability and specificity for research applications.

2. Chemical and Physical Data

Parameter

Value

Chemical Name

Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe-Tyr-Gly-Pro-Ser-Ala-Pro-Ile-Leu-OH (Modified)

Molecular Formula

C119H189N31O38S2

Molecular Weight

2588.1 g/mol

Purity

>98% (HPLC)

Appearance

White or off-white lyophilized powder

CAS Number

[AOD9604 CAS Number]

3. General Research Profile

AOD9604 was originally engineered to investigate cellular repair enhancement and regenerative characteristics. A key distinction in its research profile is its selective action: it is designed to target specific metabolic pathways without engaging the general growth hormone receptor mechanisms responsible for widespread cellular proliferation and elevated Growth Factor-1 (GF-1) concentrations.

3.1 Mechanism of Action (Hypothesized)

The compound is believed to exert its effects primarily through the induction of lipolytic activity. It is hypothesized to stimulate the expression of $\beta$-3 adrenergic receptors and increase the activity of hormone-sensitive lipase (HSL) in target cells.

3.2 Selectivity

Research indicates that AOD9604 does not significantly influence systemic Growth Factor-1 (GF-1) concentrations or glucose metabolism, presenting a unique profile for metabolic research without the risk of cellular overstimulation associated with full-length growth hormones.

4. Research Use

AOD9604 (Research Grade) is strictly for In Vitro and In Vivo laboratory investigation only.

Research Focus

Potential Applications

Metabolic Markers

Investigation into adipocyte metabolism, lipolysis, and anti-lipogenesis.

Mitochondrial Biogenesis

Study of cellular energy expenditure and the regulation of mitochondrial formation in various tissue types.

Tissue Preservation

Research into the compound's potential role in maintaining tissue integrity and modulating cellular stress responses.

Cellular Repair

Exploration of its effects on wound healing and the regeneration of specific tissue types.

5. Handling and Storage

5.1 Storage Conditions

State

Temperature

Duration

Lyophilized Powder

-20°C to -80°C

Up to 2 years

Reconstituted Solution

2°C to 8°C

7 days

Long-term Reconstituted

-20°C

Up to 3 months (Avoid repeated freeze-thaw cycles)

5.2 Reconstitution Guidelines

Reconstitute AOD9604 with sterile, bacteriostatic water or an appropriate research buffer. The recommended concentration for stock solutions is [Concentration Placeholder] mg/mL. Complete dissolution should be achieved by gentle swirling; vortexing is not recommended.

5.3 Safety and Disposal

FOR RESEARCH USE ONLY. This compound is not for human or veterinary use. Refer to the current Safety Data Sheet (SDS) before handling. Wear appropriate personal protective equipment (PPE), including gloves, lab coats, and eye protection. Dispose of all materials in accordance with institutional safety protocols and local regulations.

6. References and Supporting Documentation

Additional research data, including detailed mass spectrometry reports and High-Performance Liquid Chromatography (HPLC) data, can be found in the accompanying technical packet:

• Certificate of Analysis (CoA): File
• Safety Data Sheet (SDS): File
• Handling Protocol: File

7. Quality Assurance

Our AOD9604 (Research Grade) compound is synthesized and validated under rigorous quality assurance standards.

Quality Control Test

Specification

Purity (HPLC)

≥98%

Amino Acid Analysis

Conforms to theoretical composition

Endotoxin Level

<1 EU/mg

Microbial Testing

Sterile

For any technical inquiries or to schedule a consultation with our research team regarding specific experimental designs, please contact Person via email at [Email address placeholder] or by phone at [Phone number placeholder].

Disclaimer: This product is sold solely for use in laboratory research and is not intended for human consumption or therapeutic use. The researcher is responsible for compliance with all applicable laws and regulations.

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